Erectile Dysfunction Discussed

...everything you need and want to know about Erectile Dysfunction

  • Increase font size
  • Default font size
  • Decrease font size
Levitra

Levitra Treats ED After One Dose (Study)

LEVITRA(R) (vardenafil HCl), is effective at first dose with continued success in treating erectile dysfunction (ED) in men with associated medical conditions that affect the cardiovascular system. These conditions included high blood pressure, diabetes and/or dyslipidemia, which includes high cholesterol and other lipid abnormalities. These data were presented today at the Sexual Medicine Society of North America (SMSNA) Fall meeting and published in the November issue of the International Journal of Clinical Practice.

This randomized, placebo-controlled study involved 600 patients with diagnosed ED who received a single open-label challenge dose of LEVITRA 10 mg. Overall first dose success rates for SEP-2 (penetration) and SEP-3 (erection maintenance until completion of intercourse) during the one-week challenge period were 87 percent and 74 percent, respectively. SEP-2 first dose success was demonstrated in 84 percent of men with high blood pressure, 84 percent of men with dyslipidemia, and 75 percent of men with diabetes. Patients who achieved SEP-2 success were randomized to LEVITRA or placebo for 12 weeks. At the end of 12 weeks of treatment, study participants receiving LEVITRA 10 mg had a SEP-2 success rate of 83 percent versus 56 percent for patients receiving placebo.

"These study results demonstrate the efficacy of LEVITRA at first dose and after continued treatment in men whether or not they have associated medical conditions," said study author Luc Valiquette, MD, University of Montreal Hospital Center, Montreal, Quebec. "First-dose success and long-term reliability are important criteria for patients."

"These study results are particularly important to the nearly 30 million American men who currently suffer from ED, including the millions of men with high blood pressure, high cholesterol, and diabetes. These men are at an increased risk of developing ED," said Andrew Axilrod, MD, Director of Male Sexual Health at the University of Pennsylvania, Philadelphia.

Remainder of article can be found at Medical News Today

 

Study Confirms That Levitra® On Demand Is Effective In Patients With ED After Nerve-sparing Prostatectomy

A study published in the European Urology journal demonstrated that Levitra® (vardenafil, HCI) is highly efficacious in men with erectile dysfunction (ED) even shortly after radical nerve-sparing prostatectomy. This landmark study conducted by Bayer Schering Pharma was a double-blind, randomized, placebo-controlled multicentre study, the largest of its kind until. It investigated the tolerability and efficacy of Levitra taken once nightly as a prophylactic treatment versus Levitra PRN taken on demand (i.e. when needed) versus placebo after a bilateral, nerve-sparing, radical retropubic prostatectomy (BNSRRP).

In the first, double-blind phase of the study, which started approximately 14 days after surgery and ended nine months later, men experienced excellent results with Levitra. 36 percent of men taking Levitra on demand (on demand vs. placebo p=<0.0001), 20 percent taking Levitra nightly (p=<0.01) and 17 percent of men on placebo reported normal erectile function (represented by an International Index of Erectile Function (IIEF) of ≥ 26) measured at last observation carried forward (LOCF). Over the entire double-blind period the mean per-patient success rates for a successful intercourse were 46 percent for Levitra on demand (vs. placebo p=<0.0001), 34.5 percent for Levitra nightly, and 25 percent on placebo as measured by one question of the diary-based Sexual Encounter Profile (SEP). The study does not support its primary endpoint, the concept of maintaining erectile function by an early intervention with nightly dosing of Levitra in patients after nerve-sparing prostatectomy.

"The results show that Levitra taken on demand effectively treats erectile dysfunction immediately, and reliably after prostatectomy and helps restore the man," said lead investigator, Professor Francesco Montorsi from the University Vita Salute San Raffaele, Milan, Italy. "For men with ED caused by radical prostatectomy, this study will finally shed light on the most efficient way to use PDE5 inhibitors after this type of surgery."

Remainder of article can be found at Medical News Today

 

Everything that you should know about Levitra (vardenafil)

Written by Ajay Dumasiya
Tuesday, 07 July 2009

Very little is known about Levitra (vardenafil) as it is shadowed by two highly popular drugs, Viagra and Cialis. However, many men who have not been benefitted by the latter drugs have seen improvement in their condition with Levitra (vardenafil). Find out more about this lesser known drug for impotence below.

How Levitra works?

Vardenafil in Levitra is a phosphodiesterase type 5 inhibitor. In layman's terms, Levitra is a knight in shining armour that destroys the evil that kills good in the body. The evil is an enzyme called PDE5 and the good is a chemical called cGMP. The more of good substances in the body; the higher the chances of erection.

Levitra inhibits PDE5 and results in more production of cGMP, which helps in erection by making the penis muscles smoother leading to increased blood flow to penis and eventually resulting in an erection.

Levitra precautions

Levitra is usually safe for most men. It is even proven to be safe for men with medical conditions such as high cholesterol, high blood pressure and/or diabetes. It is the first drug to prove its safety in men with these conditions.

However, it is important to discuss your medical conditions with your doctor including heart problems and medications, including alpha-blockers prescribed for prostate problems or high blood pressure. If a doctor has advised you to refrain from sexual relations because of a heart condition, do not take Levitra. This drug is also not safe for men with uncontrolled high blood pressure. Tell all your medical conditions to your doctor during a consultation, as it is possible that Levitra may be contraindicated for you because of your condition. For instance, if you think there is no connection between eye problems and Levitra, you are wrong. Levitra is contraindicated for a rare eye condition known as retinitis pigmentosa and men with this eye condition is not allowed to take Levitra. You should avoid grapefruit and grapefruit juice with Levitra and try to keep away from high-fat foods.

Side effects of Levitra

Some common but less serious side effects of Levitra are headache, nasal stuffiness, facial flushing, stomach upset, acidity, runny nose, dizziness and/or nausea. Sometimes, it may also lead to problems with vision, such as increased sensitivity to light, blurred vision and a bluish green tinge to all objects. A very rare side effect of Levitra is a hearing defect, like ringing in the ears. These side effects are transient in nature but if they persist, do consult a doctor.

If you are allergic to vardenafil but still take the medication, you may experience reactions such as rash, itching, swelling, breathlessness and severe dizziness. Stop taking Levitra vardenafil immediately, if you experience these symptoms.

Benefits of Levitra (vardenafil)

Besides a few occasional episodes of side effects in men, Levitra vardenafil works wonderfully in almost all men without displaying serious side effects. If you take Levitra, it will help you achieve and maintain an erection followed by sexual stimulation. It starts working in 45 minutes to an hour and stays in the body for up to 9 hours in some men. What's more, it helps men despite their health problems like cholesterol, blood pressure and diabetes.

 


Main Menu

Levitra Effectiveness Survey

Levitra Effectiveness Survey
 

Latest Articles

An innovative drug-delivery system nanoparticles encapsulating nitric oxide or prescription drugs shows promise for topical treatment of erectile dysfunction (ED), according to a new study by scientists at Albert Einstein College of Medicine of Yeshiva University.

The new system, tested successfully on a small number of animals, could potentially prevent side effects associated with oral ED medications, if study results can be replicated in humans. That could mean safer and more effective ED therapy for millions of men with heart disease and other health problems affecting erectile function. The study is published today in the online edition of the Journal of Sexual Medicine.

Tens of millions of men worldwide have benefited from oral ED medications such as sildenafil (Viagra), vardenafil (Levitra), and tadalafil (Cialis). However, these medications which belong to a class of drugs called phosphodiesterase type 5 (PDE5) inhibitors have limitations. They can cause systemic side effects that can be serious. These side effects include headache, facial flushing, nasal congestion, upset stomach, abnormal vision as well as isolated reports of hearing and vision loss. Men who've recently suffered a heart attack or stroke or have severe heart disease should use these drugs with caution or not at all. In addition, "an estimated 30 to 50 percent of men with ED do not respond to oral use of PDE5 inhibitors," says senior author Kelvin P. Davies, Ph.D., associate professor of urology at Einstein.
Read more...
 

A new review of existing research suggests that group therapy can help men with erectile dysfunction even if they are already using popular drugs like Viagra. Group therapy could even be a feasible alternative to some treatments for impotence.

While the number of men studied overall was small, the reviewers found that group therapy appeared to be about as successful as suction devices and injections in terms of promoting erections. One analysis showed therapy worked for nearly two-thirds of participants.

The findings spotlight the importance of "integrating sex therapy and other psychological techniques into office practice" to help impotent patients, said lead author Tamara Melnik, professor of psychiatry at the University of São Paulo in Brazil.

The review appears in the latest issue of The Cochrane Library, a publication of The Cochrane Collaboration, an international organization that evaluates medical research. Systematic reviews draw evidence-based conclusions about medical practice after considering both the content and quality of existing medical trials on a topic.

Before the days of Viagra and its sibling drugs, many considered erectile dysfunction to be a difficult-to-treat psychological disorder. Now, drugs allow millions of men to achieve normal erections by allowing blood to flow more freely to the penis; the more serious side effects are rare.
Read more...
 

Advertising Inquiries
This e-mail address is being protected from spambots. You need JavaScript enabled to view it